Wen-Juan Ma Research

Evolutionary Genetics and Comparative Genomics

My last unpublished PhD work is now online bioRxiv

Thrilled to share my last unpublished PhD work Happy

A single QTL with large effect is associated with female functional virginity in an asexual parasitoid wasp

In this study, we investigate the genomic regions underpinning female functional virginity by QTL mapping and candidate gene analyses. Consistent with the segregation of phenotypes, our QTL analysis identified a single large-effect size QTL on LG12 at 7 or 8 cM, strongly associated with female functional virginity.

To our knowledge, this is the first study to identify candidate genes for female functional virginity, a trait that is predicted to evolve in transition from sexuality to asexuality. Overall, our results are consistent with a single gene or a cluster of linked genes underlying rapid evolution of female functional virginity in the transition to asexuality. Once a mutation for rejection to mate has swept through a population, the region comprising the gene(s) does not get smaller due to lack of recombination in asexuals.

More details and results about this article can be found here.

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GBE Cover of April issue 2020

Our illustration anther smut fungus infection of Silene latifolia made it for the GBE (Genome Biology and Evolution) April Cover.

In this paper, we found that
#DifferentialExpression between haploid mating types is associated with various degenenerious mutations,

More details and results about this article can be found here:

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Invited talk at PAG XXVIII conference in San Diego, CA, USA

I was delighted to give a talk in a fantastic section “#SexChromosomes and #SexDetermination” at the Plant and Animal Genome Conference XXVIII, #PAGXXVIII, organised by Prof. Ray Ming from University of Illinois at Urbana-Champaign. Many thanks for the invitation! Happy to talk about fungal sex chromosome evolution and #DifferentialExpression

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